What causes cancer?
Cancer
is ultimately the result of cells that uncontrollably grow and do not die.
Normal cells in the body follow an orderly path of growth, division, and death.
Programmed cell death is called apoptosis, and when this process breaks down,
cancer begins to form. Unlike regular cells, cancer cells do not experience
programmatic death and instead continue to grow and divide. This leads to a
mass of abnormal cells that grows out of control.
What are the symptoms of cancer?
Cancer
symptoms are quite varied and depend on where the cancer is located, where it
has spread, and how big the tumor is. Some cancers can be felt or seen through
the skin - a lump on the breast or testicle can be an indicator of cancer in
those locations. Skin cancer (melanoma) is often noted by a change in a wart or
mole on the skin. Some oral cancers present white patches inside the mouth or
white spots on the tongue.
Other
cancers have symptoms that are less physically apparent. Some brain tumors tend
to present symptoms early in the disease as they affect important cognitive
functions. Pancreas cancers are usually too small to cause symptoms until they
cause pain by pushing against nearby nerves or interfere with liver function to
cause a yellowing of the skin and eyes called jaundice. Symptoms also can be
created as a tumor grows and pushes against organs and blood vessels. For
example, colon cancers lead to symptoms such as constipation, diarrhea, and
changes in stool size. Bladder or prostate cancers cause changes in bladder
function such as more frequent or infrequent urination.
As
cancer cells use the body's energy and interfere with normal hormone function,
it is possible to present symptoms such as fever, fatigue, excessive sweating,
anemia, and unexplained weight loss. However, these symptoms are common in
several other maladies as well. For example, coughing and hoarseness can point
to lung or throat cancer as well as several other conditions.
When
cancer spreads, or metastasizes, additional symptoms can present themselves in
the newly affected area. Swollen or enlarged lymph nodes are common and likely
to be present early. If cancer spreads to the brain, patients may experience
vertigo, headaches, or seizures. Spreading to the lungs may cause coughing and
shortness of breath. In addition, the liver may become enlarged and cause
jaundice and bones can become painful, brittle, and break easily. Symptoms of
metastasis ultimately depend on the location to which the cancer has spread.
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